通过“干湿结合”的模式，长期从事过敏性哮喘和肺损伤等炎性呼吸疾病的免疫学和组学研究，研究方向包括：

1.儿童过敏性哮喘中神经免疫调节机制；

2.多组学分析鉴定儿童过敏性哮喘激素耐受机制和药物新靶点；

3.CRISPR筛选哮喘和肺感染中组织定居记忆性T细胞关键调控因子；

4.靶向组织定居记忆性T细胞关键调控因子小分子药物筛选。

代表性学术论文：

1. Kamakshi Bankoti*, Wei Wang*, Gaurang M. Amonkar, Linjie Xiong, Jessica E. Shui, Mwase Chimwemve, Jin-Ah Park, Hongmei Mou, Yinshan Fang, Jianwen Que, Yan Bai, Paul H. Lerou and Xingbin Ai. Airway basal stem cells in COVID-19 exhibit a proinflammatory signature and impaired mucocililary differentiation. American Journal of Respiratory Cell and Molecular Biology (IF=6.4). 2024 Jan;70(1):26-38. (co-first author)

2. Jianye Deng*, Hong-Jin Zhao*, Ying Zhong*, Cuiping Hu, Shiqin Zhu, Jinlai Meng, Chunling Wang, Xiangxin Lan, Xiyao Wang, Zi-Jiang Chen, Junhao Yan^†, Wei Wang^†, Yan Li^†. H3K27me3-regulated Human Trophoblast BMP2 Signaling Enhancement Can Alleviate Shallow Trophoblast Invasion in Preeclampsia. eBioMedicine (IF=11.1). 2023 Jun 16;93:104664. (Co-corresponding author)

3. Wei Wang*^†, Carolyn Garcia, Fengzhi Shao, Jonathan A. Cohen, Yan Bai, Alan Fine and Xingbin Ai. Lung dopaminergic nerves facilitate the establishment of T_H2 resident memory cells in early life. Journal of Allergy and Clinical Immunology (IF=14.2). 2023 Aug 3;152(23):386-99. (First author and co-corresponding author)

4. Wei Wang*, Jonathan A. Cohen, Antonia Wallrapp, Kenneth G. Trieu, Juliana Barrios, Fengzhi Shao, Nandini Krishnamoorthy, Vijay K. Kuchroo, Matthew R. Jones, Alan Fine, Yan Bai, Xingbin Ai. Age-related dopaminergic innervation augments T helper 2-type allergic inflammation in the postnatal lung. IMMUNITY (IF=32.4). 2019 Dec 17;51(6):1102-1118.e7.

5. Wei Wang*^†, Xingbin Ai. Primary culture of immature, naïve mouse CD4⁺ T cells. STAR Protocols. 2021 Aug 14;2(3):100756. (First author and co-corresponding author)

6. Wei Wang*, Penghui Yang*, Ying Zhong*, Zhongpeng Zhao, Li Xing, Yan Zhao, Zhen Zou,  Yanli Zhang, Chenggang Li, Taisheng Li, Chen Wang, Zhong Wang, Xuezhong Yu, Bin Cao, Xiang Gao, Josef M. Penninger, Xiliang Wang and Chengyu Jiang. Monoclonal antibody against CXCL-10/IP-10 ameliorates influenza A (H1N1) virus induced acute lung injury. Cell Research (IF=44.1). 2013 Apr;23(4):577-80.

7. JingGuo*, Fengming Huang*, Jun Liu*, Yu Chen*, Wei Wang*, Bin Cao*, Zhen Zou, Song Liu, Jingcao Pan, Changjun Bao, Mei Zeng, Haixia Xiao, Hainv Gao, Shigui Yang, Qiang Liu, Huandi Zhou, Jingdong Zhu, Xiaoli Liu, Weifeng Liang, Yida Yang, Shufa Zheng, Jiezuan Yang, Hongyan Diao, Kunkai Su, Li Shao, Hongcui Cao, Ying Wu, Min Zhao, Shuguang Tan, Hui Li, Xiaoqing Xu, Chunmei Wang, Jianmin Zhang, Li Wang, Jianwei Wang, Jun Xu, Dangsheng Li, Nanshan Zhong, Xuetao Cao, George F. Gao, Lanjuan Li and Chengyu Jiang. The Serum Profile of Hypercytokinemia Factors Identified in H7N9-Infected Patients can Predict Fatal Outcomes. Scientific Reports (IF=4.6). 2015 Jun 1;5:10942. (Co-first author)

完整的已发表论文：https://www.ncbi.nlm.nih.gov/myncbi/wei.wang.38/bibliography/public/

专利：

1. Application of inhibitor of CXCL-10 in preparation of drug for treatment and/or prevention of lung injury. China Patent Application, CN103417967B.

2. Application of IL-17 inhibitor in preparation of drug for treating and/or preventing lung injury. Worldwide Patent Application, WO2012113343A1.

博士，呼吸疾病全国重点实验室PI，南山学者特聘教授，博士生导师。2015年在北京协和医学院获得博士学位。随后前往哈佛医学院进行博士后培训，2022年晋升为讲师。2024年全职加入呼吸疾病国家重点实验室。迄今为止，在国际权威期刊发表SCI论文16篇，累计引用超1100次；其中以第一作者（含共同）和共同通讯作者发表SCI论文6篇，中科院I区的有5篇，包括Immunity，Cell Research，Journal of Allergy and Clinical Immunology，eBioMedicine和American Journal of Respiratory Cell and Molecular Biology。获得专利授权2项；担任Comparative Immunology, Microbiology & Infectious Diseases和Infectious Medicine期刊的编委。